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Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Nucleotide (GenBank) : AJ238108 Acremonium chrysogenum cah gene, exons 1-3.
Hollander IJ, et al. A pure enzyme catalyzing penicillin biosynthesis. Science 224: 610-612, 1984. PubMed: 6546810
Shen YQ, et al. Levels of isopenicillin N synthase and deacetoxycephalosporin C synthase in Cephalosporium acremonium producing high and low levels of cephalosporin C. Bio-Technology 4: 61-64, 1986.
Zhang J, et al. Carbon source regulation of ACV synthetase in Cephalosporium acremonium C-10. Curr. Microbiol. 18: 361-367, 1989.
Malmberg LH, Hu WS. Identification of rate-limiting steps in cephalosporin C biosynthesis in Cephalosporium acremonium: a theoretical analysis. Appl. Microbiol. Biotechnol. 38: 122-128, 1992. PubMed: 1369008
Zhang J, Demain AL. Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway of carbon sources and their metabolites. Arch. Microbiol. 158: 364-369, 1992.
Luengo JM, et al. Direct enzymatic synthesis of penicillin G using cyclases of Penicillium chrysogenum and Acremonium chrysogenum. Bio-Technology 4: 44-47, 1986.
Shen YQ, et al. Desacetoxycephalosporin C synthetase: importance of order of cofactor/reactant addition. Enzyme Microb. Technol. 6: 402-404, 1984.
