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HP6017
HP6017
規(guī)格:
價(jià)格:
編號(hào):B164634
品牌:Mingzhoubio

標(biāo)準(zhǔn)菌株
定量菌液
DNA
RNA

規(guī)格:
凍干粉
斜面
甘油
平板


產(chǎn)品名稱
HP6017
商品貨號(hào)
B164634
Organism
Mus musculus (B cell); Mus musculus (myeloma), mouse (B cell); mouse (myeloma)
Cell Type
hybridoma: B lymphocyte
培養(yǎng)基
Product Format
frozen
Morphology
lymphoblast
Culture Properties
suspension
Biosafety Level
1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Strain
BALB/c (B cell); BALB/c (myeloma)
Applications
The antibody produced by this cell line was selected as a reference reagent of the WHO Collaborating Center at the Centers for Disease Control for Human Immunoglobulin Subclasses.
Storage Conditions
liquid nitrogen vapor phase
Derivation
Animals were immunized with purified human immunoglobulin.

Spleen cells were fused with Sp2/0-Ag14 myeloma cells.

Genes Expressed
immunoglobulin; monoclonal antibody; against human IgG (Fc)
Cellular Products
immunoglobulin; monoclonal antibody; against human IgG (Fc)
Comments
Antibody reacts with human IgG (all four IgG subclasses) and cross-reacts with IgG from rabbit, goat, sheep and horse.

The antibody does not react with human Fab or F(ab')2 nor does it react with human IgA, IgE or IgM.

Tested and found negative for ectromelia virus (mousepox).

Complete Growth Medium

The base medium for this cell line is ATCC-formulated Dulbecco's Modified Eagle's Medium, (ATCC 30-2002). To make the complete growth medium, add the following components to the base medium:

  • 10 mM HEPES
  • 0.05 mM 2-Mercaptoethanol
  • Fetal Bovine Serum (FBS; ATCC 30-2020) to a final concentration of 10%
Subculturing
Cultures can be maintained by addition or replacement of fresh medium. Establish new cultures at 2 x 105 cells/mL and maintain between 1 x 105 and 1 x 106 cells/mL.
Medium Renewal: Every 2 to 3 days
Cryopreservation
Culture medium, 95%; DMSO, 5%
Isotype
IgG2a
Name of Depositor
CB Reimer
Deposited As
mouse (B cell); mouse (myeloma)
References

Reimer CB, et al. Evaluation of thirty-one mouse monoclonal antibodies to human IgG epitopes. Hybridoma 3: 263-275, 1984. PubMed: 6209201

Jefferis R, et al. Evaluation of monoclonal antibodies having specificity for human IgG sub-classes: Results of an IUIS/WHO collaborative study. Immunol. Lett. 10: 223-252, 1985. PubMed: 3899923

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