最新中文字幕-精品国产99-国产精品福利在线观看-粉嫩av一区二区三区-日韩精品久久久久-美丽的姑娘国语视频-亚洲欧洲色-国产不卡毛片-三级黄毛片-免费福利在线-日韩av三区-欧美成年人网站-欧洲美女与动交ccoo-成人涩涩软件-秋霞影院午夜老牛影院-婷婷久久伊人-呦呦视频在线观看-www.天天综合-日韩精品高清视频-国产欧美综合在线-欧美日韩一区二区三区在线视频-a猛片免费播放-91九色蝌蚪国产-国产欧美日韩专区-嫩模被强到高潮呻吟不断

歷史搜索:A549    293T 金黃色葡萄球菌 大腸桿菌 AKK菌
購物車 1 種商品 - 共0元
當前位置: 首頁 > ATCC代理 > AP-3 B163951
AP-3
AP-3
規格:
價格:
編號:B163951
品牌:Mingzhoubio

標準菌株
定量菌液
DNA
RNA

規格:
凍干粉
斜面
甘油
平板


產品名稱
AP-3
商品貨號
B163951
Organism
Mus musculus (B cell); Mus musculus (myeloma), mouse (B cell); mouse (myeloma)
Cell Type
hybridoma: B lymphocyte
培養基
Product Format
frozen
Morphology
lymphoblast
Culture Properties
suspension
Biosafety Level
1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Disease
Leukemia
Strain

Strain:? BALB/c (B cell); BALB/c (myeloma)

Applications
The antibody reacts specifically with GPIIIa, but does not inhibit platelet aggregation.
It is useful for studies of human GPIIIa expression by flow cytometry, Western blot (non-reduced) and affinity chromatography methods.
The antibody can also be used for the classification of human megakaryocytic leukemias and Glanzmann thrombasthenia.
Derivation
Animals were immunized with partially purified human platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa, respectively).
Spleen cells were fused with NS-1 myeloma cells.
Genes Expressed
immunoglobulin; monoclonal antibody; against beta 3 integrin (platelet GPIIIa)
Cellular Products
immunoglobulin; monoclonal antibody; against beta 3 integrin (platelet GPIIIa)
Comments
Animals were immunized with partially purified human platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa, respectively).
Spleen cells were fused with NS-1 myeloma cells.
The antibody recognizes all known allelic forms of the beta 3 subunit of the integrin superfamily.
The two glycoproteins (GPIIb and GPIIIa) together form the platelet binding site for fibrinogen.
The antibody reacts specifically with GPIIIa, but does not inhibit platelet aggregation.
It is useful for studies of human GPIIIa expression by flow cytometry, Western blot (non-reduced) and affinity chromatography methods.
The antibody can also be used for the classification of human megakaryocytic leukemias and Glanzmann thrombasthenia.
Complete Growth Medium
The base medium for this cell line is ATCC-formulated RPMI-1640 Medium, Catalog No. 30-2001. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%.
Subculturing
Medium Renewal: Every 2 to 3 days
Cultures can be maintained by addition or replacement of fresh medium. Start cultures at 2 X 10 exp5 cells/ml and maintain between 1 X 10 exp5 and 1 X 10 exp6 cells/ml.
Isotype
IgG1
Name of Depositor
PJ Newman
Deposited As
mouse (B cell); mouse (myeloma)
References

Newman PJ, et al. Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. Blood 65: 227-232, 1985. PubMed: 3155488

Newman PJ, et al. Synergistic action of two murine monoclonal antibodies that inhibit ADP- induced platelet aggregation without blocking fibrinogen binding. Blood 69: 668-676, 1987. PubMed: 3026525

Isenberg WM, et al. Monoclonal antibodies bound to subunits of the integrin GPIIb-IIIa are internalized and interfere with filopodia formation and platelet aggregation. Blood 76: 1564-1571, 1990. PubMed: 2207330

  • 王經理
    手機號：17280875617
    QQ：1438578920
  • 胡經理
    手機號：13345964880
    QQ：2438244627
  • 周經理
    手機號：17757487661
    QQ：1296385441
  • 于經理
    手機號：18067160830
    QQ：2088210172
  • 沈經理
    手機號：19548299266
    QQ：2662369050
  • 李經理
    手機號：13626845108
    QQ：972239479